Figure 2.
Summary of methodology and result interpretation. a: The work-flow of the current analysis: In the pictorial representation, the W and P represents the wild and polymorphic alleles on the 201st position, TS and TE represent the target site start and end. The secondary structure obtained for the 400 nt stretch is in the form of brackets (representing structured bases) and dots (representing unbound bases). b: Screen-shot of query result with miRNA hsa-let-7f. b: A result display of the database. The columns give the information as target gene name, miRNA target the transcript, the transcript ID, the location of miRNA binding with respect to the 3' UTR of the transcript, the binding modality, the location of SNP with respect to the target site, the SNP ID, the number of bases changing intramolecular conformation, the effect of the change (as gain or loss), and a link-out to pictorial depiction of the structural change.