Table 3.

Odds ratios (OR) and 95% confidence intervals (CI) for the association between mitochondrial haplogroup and CAD and Valvular Heart Disease, respectively.

	Haplogroup	OR* (95% CI)	p-value	aOR† (95% CI)	p-value
Coronary artery disease
	H	1 (ref)		1 (ref)
	U	1.06 (0.69–1.61)	0.791	1.18 (0.72–1.93)	0.504
	J	0.92 (0.58–1.47)	0.738	1.09 (0.63–1.89)	0.766
	T	2.36 (1.52–3.65)	< 0.0005‡	2.33 (1.37–3.98)	0.002‡
Valvular Heart disease
	H	1 (ref)
	U	1.05 (0.50–2.17)	0.903
	J	0.96 (0.44–2.14)	0.930
	T	1.24 (0.52–2.96)	0.626

*Adjusted for age and sex (CAD n = 382, Valvular heart disease n = 93, controls n = 1203); ^†adjusted for age, sex, smoking, hypertension, and body mass index (CAD n = 345, controls n = 1095); ^‡Bonferroni-corrected statistical significance: p < 0.05/3 × 2 = < 0.008.