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. 2009 Mar 31;10:142. doi: 10.1186/1471-2164-10-142

Table 1.

Description of genes analyzed in skeletal muscle tissue.

Gene symbol1 Cellular localization Biological process
ACACA Cytoplasm Fatty acid biosynthesis
ACLY Cytosol Citrate metabolic process
ACSL1 Plasma and ER membranes Fatty acid metabolism
AGPAT1 ER membrane Phosphatidic acid biosynthesis
CD36 Plasma membrane Fatty acid metabolism
DGAT1 ER membrane Triacylglycerol metabolism
DGAT2 ER membrane Triacylglycerol metabolism
FABP4 Cytosol Fatty acid binding, transport
FADS2 ER membrane Unsaturated fatty acid synthesis
FASN Cytosol Fatty acid biosynthesis
G6PD Cytosol Pentose-phosphate shunt
GPAM Cytosol, mitochondria Triacylglycerol biosynthesis
INSIG1 ER membrane Lipid metabolism, cell proliferation
INSR Plasma membrane Insulin receptor signaling
IRS1 Cytosol Insulin receptor signaling
LPIN1 Nucleus, ER, cytosol Phosphatidic acid hydrolysis, transcription
LPIN2 ER, cytosol Phosphatidic acid hydrolysis
LPIN3 ER, cytosol Phosphatidic acid hydrolysis
MDH2 Mitochondrial matrix Tricarboxylic acid cycle, malate metabolic process
PPARD Nucleus Fatty acid beta-oxidation, transcription
PPARG Nucleus Induction of adipocyte differentiation, transcription
PPARGC1A Nucleus Fatty acid beta-oxidation, transcription factor
PPARGC1B Nucleus DNA-dependent regulation of transcription
PRKAA1 Cytosol Fatty acid biosynthesis, signal transduction
PRKAA2 Cytosol Fatty acid biosynthesis, signal transduction
SCAP ER membrane, Golgi SREBP target gene transcription activation
SCD ER membrane Fatty acid biosynthesis
SLC27A1 Plasma and ER membranes Fatty acid transport
SLC2A4 Plasma membrane, cytosol Glucose transport, glucose homeostasis
SREBF1 Golgi and ER membranes, nucleus Transcription regulation
THRSP Nucleus Lipid metabolic process

1Entrez Gene, National Center for Biotechnology Information (NCBI)