Table 3.

Comparison of residues implicated in sulphate binding

	CSA-binding DBL domains							Non-binders
A4 3X	3D7 3X	2X		5ε		6ε		A4 4ε	3D7 1X
		A4	3D7	A4	3D7	A4	3D7
Sulfate binding residues
K 1324*	R	-	-	-	-	-	-	H	-
G 1329*	G	-	-	K	-	-	-	-	-
R1467*	Q	A	E	E	E	K	E	K	N
K1504 #	K	E	K	E	E	A	A	A	K
Residues within 5Å of modelled CSA
K1327#	M	-	K	-	K	-	-	-
R1503#	R	D	N	S	S	H	E	K	D
K1507#	E	K	V	K	K	N	N	N	K
K1510#	K	K	K	E	E	N	N	N	E

• [10,11].

• Conserved residues are in bold, acidic residues are in italics and underlined and other residues are bold and underlined.