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. Author manuscript; available in PMC: 2009 May 3.
Published in final edited form as: Nat Protoc. 2008;3(3):388–397. doi: 10.1038/nprot.2007.537

Figure 4.

Figure 4

Schematic of vessel wall thickening by precursor cells in the rat after high oxygen (left); values for gold-labeled antigenic sites quantified by macro for each cell population at each time point (right). Note the distribution of sites in the normal lung (Control, D0) and the shift early (D4) and late (D28) in the hypertensive lung; although PDGF-AA expression predominates in vascular cells of the normal lung, a shift to PDGF-Rβ expression begins in the early stage of pulmonary hypertension and is pronounced in the late stage (reprinted with permission from ref. 4, Jones et al., 2006).