Table 1.
Patient characteristics and outcomes according to autologous versus allogeneic transplant
| Characteristic | Autologous (N=56) | Allogeneic (N=165) |
|---|---|---|
| Age (years) | 41.3 ± 15.3 | 39.3 ± 13.2 |
| Female patients | 22 (39) | 58 (35) |
| Donor type | ||
| Autologous | 56 (100) | - |
| Related, matched | - | 83 (50) |
| Related, mismatched | - | 23 (14) |
| Unrelated | - | 59 (36) |
| Diagnosis | ||
| Acute leukemia | 5 (8) | 83 (50) |
| Chronic leukemia | 0 (0) | 28(17) |
| Hodgkin’s lymphoma | 14 (22) | 7 (4) |
| Non-Hodgkins lymphoma | 14 (22) | 10 (6) |
| Multiple myeloma | 13 (20) | 8 (5) |
| Myelodysplastic syndrome | 0 (0) | 20 (12) |
| Other | 10 (18) | 9 (5) |
| Disease status | ||
| Accelerated phase | 0 (0) | 8 (6) |
| Blast crisis | 0 (0) | 9 (6) |
| Chronic phase | 0 (0) | 8 (6) |
| De novo | 1 (2) | 5 (3) |
| Relapse | 42 (75) | 78 (55) |
| Remission | 12 (21) | 33 (23) |
| Unknown | 1 (2) | 2 (1) |
| Percent of predicted DLCO | 55.5% (34%–60%) | 54% (19%–60%) |
| Percent of predicted DLCO category | ||
| 50–60% | ||
| 40–50% | 49 (87) | 118 (71) |
| <40% | 6 (11) | 34 (21) |
| 1 (2) | 13 (8) | |
| Respiratory failure | 10 (18) | 56 (34) |
| Nonrelapse mortality | 27 (48) | 104 (63) |
Numbers represent either mean ± standard deviation, median (range), or count (%).