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. 2009 May;10(5):331–340. doi: 10.1631/jzus.B0820248

Table 2.

Characteristics, treatment times, and local responses of the gene-receiving patients

Patient No. Gender Age (year) Histology Stage Gene transfer access rAd-p53
BAI times Local response TTP (month) Survival duration (month)
Time Dose (×1012 VP)
1 M 40 Adeno IIIa TA 2 2 3 SD 9 12
2 M 56 Squam IIIb TA 2 1 2 SD 6 8
3 M 39 Adeno IIIa PI 3 2 3 PD 1 2
4 M 51 Large cell IIIb PI 2 2 2 PR 10 12
5 M 53 Squam IIIa PI/TA 4 3 4 CR 13 12
6 M 71 Adeno IV PI & TC 2 2 1 SD 5 9
7 M 80 Adeno IV PI 2 1 2 SD 6 7
8 M 48 Adeno IIIb PI & LN 2 3 3 PR 7 12
9 F 56 Squam IV TA 2 4 4 SD 4 7
10 F 72 Large cell IV PI 3 3 2 PD 2 3
11 M 74 Squam IV PI 1 1 2 SD 5 6
12 M 61 Adeno Squam IIIb PI 4 1 2 PR 7 11
13 F 54 Adeno IIIa TA 2 3 3 PR 9 12
14 F 53 Adeno IV TA 3 2 3 PR 6 8
15 M 54 Squam IIIb TA 4 2 2 CR 13 12
16 M 59 Squam IIIa PI 4 2 2 PR 11 12
17 M 79 Squam IV TA 2 1 2 PR 7 12
18 M 46 Squam IIIa TA 3 2 3 PR 8 12
19 M 68 Squam IIIa TA 2 2 1 PR 10 12

M: male; F: female; Adeno: adenocarcinoma; Squam: squamous; TA: transarterial infusion; TC: thoracic cavity; PI: percutaneous injection; LN: lymph nodes; BAI: bronchial arterial infusion; SD: stable disease; PD: progressive disease; PR: partial response; CR: complete response; TTP: time to progression