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Effect of different doses of cytosolic vitamine E on mitochondrial Ca2+ homeostasis. HeLa cells were transfected with the mtAeqmut probe, treated with (A) 5 μmol/L or (B) 20 μmol/L unmodified vitamine E (α-tocopherol), and then stimulated with 10 μmol/L histamine. No major difference on the amplitude and kinetics of the [Ca2+]m rise is observed compared to untreated cells.
