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Effect of triphenylphosphonium cation (TPP+) on mitochondrial Ca2+ homeostasis. HeLa cells were transfected with mtAeqmut probe, treated with TPP+ 5 μmol/L, and then stimulated with 10 μmol/L histamine. The amplitude of the [Ca2+]m rise is increased in TPP+ treated cells and the return to basal levels significantly delayed.
