Table 3. Tumour marker accuracy and sensitivity at 95% specificity for ovarian cancer and ovarian endometriosis.
| Markers | Accuracy (%) | ROC-AUC (%) | Sensitivity (%) |
|---|---|---|---|
| OvCa vs OvEndo | |||
| CA125+HE4 | 94.0 | 91.3 | 78.6 |
| CA125 | 92.8 | 77.0 | 64.3 |
| HE4 | 91.6 | 91.9 | 71.4 |
| OvCa vs ctrl | |||
| CA125+HE4 | 96.3 | 91.1 | 92.9 |
| CA125 | 96.3 | 91.7 | 78.6 |
| HE4 | 93.8 | 95.5 | 78.6 |
| OvEndo vs ctrl | |||
| CA125+HE4 | 82.2 | 86.8 | 62.3 |
| CA125 | 83.0 | 87.7 | 60.9 |
| HE4 | 60.7 | 60.5 | 5.8 |
| OvCa vs OvEndo vs ctrl | |||
| CA125+HE4 | 81.9 | ||
| CA125 | 81.2 | ||
| HE4 | 59.7 | ||
OvCa=ovarian cancer; OvEndo=ovarian endometriosis.