Table 4. Levels of N7-meG (fmol μg−1 DNA) in DNA extracted from tumour samples from patients in the treatment groups indicated and as described in the Patients and Methods section.
Sampling time | LM/TMZ | TMZ alone | LM/TMZ on progression |
---|---|---|---|
Day 6 | |||
N | 4 | 1 | 2 |
Mean | 36.0 | 40.1 | 50.6 |
Range | 27.8–49.6 | — | 47.9–53.2 |
Day 7 | |||
N | 1 | 1 | 1 |
Value | 38.8 | 40.4 | 33.3 |
Day 8 | |||
N | 1 | — | — |
Value | 25.6 | — | — |
Abbreviations: LM=lomeguatrib; TMZ=temozolomide.