Table 3.
Risk of Preterm Delivery and SGA With Elevated cFN and Hyperuricemia
| Risk of Preterm Delivery (<37 wk) | Risk of SGA (<10th Centile) | |||||||
|---|---|---|---|---|---|---|---|---|
| Group | n | Unadjusted Prevalence | Adjusted ORa | 95% CI | Unadjusted Prevalence | Adjusted ORa | 95% CI | |
| Normotensive | N | 316 | 7.9 | 1.0 | Referent | 7.0 | 1.0 | Referent |
| Elevated cFN | C | 102 | 2.9 | 0.3 | 0.1-1.1 | 11.5 | 1.7 | 0.8-3.4 |
| Hyperuricemia | U | 126 | 5.6 | 0.6 | 0.3-1.4 | 8.7 | 1.1 | 0.5-2.3 |
| Hyperuricemia and elevated cFN | UC | 61 | 9.8 | 1.2 | 0.5-2.9 | 4.9 | 0.8 | 0.2-2.6 |
| Hypertension only | H | 83 | 3.6 | 0.4 | 0.1-1.3 | 10.8 | 1.3 | 0.6-3.3 |
| Hypertension and elevated cFN | HC | 21 | 9.5 | 1.0 | 0.2-4.4 | 9.5 | 1.3 | 0.3-6.1 |
| Hypertension and hyperuricemia | HU | 36 | 22.2 | 3.1 | 1.3-7.5 | 19.4 | 3.4 | 1.3-8.7 |
| Hypertension, hyperuricemia, elevated cFN | HUC | 31 | 16.1 | 2.0 | 0.7-5.6 | 19.4 | 2.7 | 0.9-7.8 |
| Preeclampsia | HP | 37 | 10.8 | 1.3 | 0.4-3.9 | 16.2 | 2.0 | 0.7-5.8 |
| Preeclampsia and elevated cFN | HPC | 28 | 13.8 | 1.7 | 0.5-5.2 | 13.8 | 2.7 | 0.9-8.6 |
| Preeclampsia and hyperuricemia | HPU | 42 | 42.9 | 8.0 | 3.8-16.4 | 16.7 | 2.7 | 1.1-6.7 |
| Preeclampsia, hyperuricemia, and elevated cFN | HPUC | 80 | 58.2 | 14.7 | 8.1-26.7 | 30.4 | 6.8 | 3.5-13.1 |
Abbreviations: cFN, cellular fibronectin; CI, confidence interval; OR, odds ratio; SGA, small for gestational age.
a
Adjusted for prepregnancy body mass index and smoking.