Table 4.
Relation Between Elevated Cellular Fibronectin (cFN) and Hyperuricemia and Length of Gestation and Birth Weight Centile
| Gestational Age at Delivery | Birth Weight Centile | |||||||
|---|---|---|---|---|---|---|---|---|
| Group | n | Unadjusted Gestational Age at Deliverya | Adjusted Coefficientb | P | Unadjusted Birth Weight Centilea | Adjusted Coefficientb | P | |
| Normotensive | N | 316 | 38.9 (2.5) | Referent | 49.5 (27.6) | Referent | ||
| Elevated cFN | C | 102 | 39.2 (1.3) | 0.43 | .11 | 51.5 (29.6) | 0.84 | .77 |
| Hyperuricemia | U | 126 | 39.2 (1.7) | 0.40 | .11 | 51.8 (28.3) | 2.46 | .41 |
| Hyperuricemia and elevated cFN | UC | 61 | 38.6 (1.7) | –0.19 | .57 | 52.8 (29.6) | 0.91 | .82 |
| Hypertension only | H | 83 | 39.1 (1.3) | 0.23 | .44 | 48.3 (30.5) | –4.30 | .22 |
| Hypertension and elevated cFN | HC | 21 | 39.0 (1.6) | 0.15 | .79 | 45.1 (29.4) | –5.27 | .39 |
| Hypertension and hyperuricemia | HU | 36 | 38.2 (2.2) | –0.69 | .10 | 40.5 (31.8) | –12.49 | .01 |
| Hypertension, hyperuricemia, elevated cFN | HUC | 31 | 38.3 (2.3) | –0.43 | .34 | 45.9 (32.4) | –5.54 | .30 |
| Preeclampsia | HP | 37 | 38.2 (2.0) | –0.62 | .14 | 48.0 (32.6) | –3.44 | .48 |
| Preeclampsia and elevated cFN | HPC | 28 | 38.1 (2.1) | –0.80 | .09 | 39.6 (28.9) | –14.14 | .01 |
| Preeclampsia and hyperuricemia | HPU | 42 | 36.0 (4.1) | –2.88 | <.01 | 36.4 (28.9) | –15.13 | <.01 |
| Preeclampsia, hyperuricemia, and elevated cFN | HPUC | 80 | 34.8 (3.8) | –4.03 | <.01 | 31.4 (27.2) | –21.43 | <.01 |
a
Mean (SD).
b
Adjusted for prepregnancy body mass index and smoking. Each coefficient represents the change in the gestational age at delivery (weeks) or birth weight centile associated with having gestational hypertension, proteinuria, hyperuricemia, and/or elevated cFN compared with normotensive women.