Table 2.
Effects of KM+ treatment on proliferation cell nuclear antigen (PCNA), p63, vascular endothelial growth factor (VEGF), c-Met and laminin labelling, after 12 and 24 h of corneal abrasion in rabbits
Groups | PCNA | P63 | VEGF | c-Met | Laminin | |
---|---|---|---|---|---|---|
12 h | KM+ (n = 5) | 1.9 ± 0.2 | 2.2 ± 0.3 | 1.1 ± 0.2 | 6.1 ± 0.4 | 4.6 ± 0.1 |
Control (n = 5) | 1.5 ± 0.5 | 2.5 ± 0.1 | 0.8 ± 0.5 | 5.9 ± 0.2 | 4.1 ± 0.4 | |
24 h | KM+ (n = 10) | 47.4 ± 0.4* | 46 ± 0.5* | 29.5 ± 0.7* | 74.5 ± 0.6* | 42.5 ± 0.5* |
Control (n = 10) | 27.6 ± 0.2 | 5.7 ± 0.4 | 2.4 ± 0.5 | 7.3 ± 0.4 | 4.8 ± 0.5 |
PCNA, p63, VEGF, c-Met and laminin labelling were expressed as percentage of positive labelling ± SEM.
Significantly different compared to controls (P < 0.05 Fisher's exact test).