Table 1.
Summary of animal weight, age, plethysmography data, exposure dose and time to death data
| Step (Dixon method) | Gender | Age (years) | Body weight (g) | Accumulative volume (l) | Aerosol concentration (CFU/l) | Inhaled dose (CFU) | Time to death [hours (days)] |
|---|---|---|---|---|---|---|---|
| Step 1 | M | 5.1 | 400 | NA | 180 | NA | 133.5 (5.5) |
| F | 3.3 | 382 | NA | 280 | NA | 132.5 (5.5) | |
| Step 2 | M | 3.4 | 364 | 0.5 | 17 | 9 | 204 (8.5) |
| F | 2.0 | 360 | 0.2 | 18 | 4 | 319 (13) | |
| Step 3 | M | 3.3 | 364 | 0.9 | 44 | 40 | 107 (4.5) |
| F | 1.6 | 484 | 1.0 | 65 | 66 | 120 (5) | |
| M | 3.3 | 410 | 2.0 | 130 | 260 | 118 (5) | |
| F | 1.5 | 398 | 0.9 | 150 | 130 | 167 (7) | |
| M | 5 | 404 | 0.9 | 190 | 180 | 162 (6.5) | |
| F | 2.2 | 380 | 1.5 | 190 | 300 | 105 (4.5) |
NA, not available.