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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: J Mol Biol. 2009 Mar 13;388(2):239–251. doi: 10.1016/j.jmb.2009.03.017

Fig. 1. In vitro determination of enhancer elements.

Fig. 1

(a) Region D (but not C) increased activity of the human AgRP promoter, equally in the human adrenocortical NCI-h295R and the mouse clonal hypothalamic N38 cell lines. (b) Region D was divided into 3 sub-regions of which only Di and Diii increased basal promoter activity in both cell lines.