Skip to main content
. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: J Mol Biol. 2009 Mar 13;388(2):239–251. doi: 10.1016/j.jmb.2009.03.017

Fig. 8. Comparative analysis of human and mouse AgRP-ATP6V0D1 loci.

Fig. 8

(a) Schematic representation of the human and mouse syntenic AgRP/ATP6V0D1 loci indicating the identity scores (percent) for exons and introns between the two species and presence of enhancers Diiia and Diiib in human only. (b) Algorithmic analysis comparing the CpG islands between the human and mouse syntenic loci encompassing the AgRP-ATP6V0D1 genes. The human AgRP-ATP6V0D1 locus contains three separate CpG islands whereas the mouse locus contains a single continuous CpG island. Enhancers Diiia and Diiib were found to be inside the gap between the second and third CpG islands.