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. Author manuscript; available in PMC: 2009 May 4.
Published in final edited form as: Curr Pharmacogenomics Person Med. 2008;6(3):150–159. doi: 10.2174/1875692110806030150

Fig. (3).

Fig. (3)

Physiologic product distribution, for an enzymatic decision pointwhere substrate affinity for isoform 1 > isoform 2 > isoform 3. Despite the presence of SNPs in key enzymes, the relative product distribution is largely unchanged under physiologic conditions (i.e., relative phenotypic homogeneity).