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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Gastroenterol Clin North Am. 2008 Sep;37(3):685–ix. doi: 10.1016/j.gtc.2008.06.002

Table 1.

Cardinal Features of Chronic Functional Anorectal and Urogynecological Disorders

Disorders are diagnosed by symptoms, supplemented by objective findings in interstitial cystitis
Predominant symptom is discomfort or pain; patients may also have dysfunctional voiding or defecation
Frequently associated with impaired quality of life, anxiety, and depression
Pathophysiology is barely studied and poorly understood; visceral hypersensitivity and pelvic floor dysfunction may play a role
Therapy is guided by clinical features. Therapeutic approaches have not been rigorously tested in clinical trials