Table 1.
Disorders are diagnosed by symptoms, supplemented by objective findings in interstitial cystitis |
Predominant symptom is discomfort or pain; patients may also have dysfunctional voiding or defecation |
Frequently associated with impaired quality of life, anxiety, and depression |
Pathophysiology is barely studied and poorly understood; visceral hypersensitivity and pelvic floor dysfunction may play a role |
Therapy is guided by clinical features. Therapeutic approaches have not been rigorously tested in clinical trials |