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Percentage reduction of plasma glucose concentration in diabetic rats after administration of insulin-loaded SLN 50 IU/kg (▴), subcutaneous injection of insulin 2.5 IU/Kg (○) and oral insulin solution 50 IU/kg (▪). Data represents the mean ± SEM, n = 6 per group. *Statistically significant differences from oral insulin solution (p < 0.05).
