Skip to main content
. Author manuscript; available in PMC: 2009 May 4.
Published in final edited form as: Popul Dev Rev. 2008 Sep 5;34(3):457–482. doi: 10.1111/j.1728-4457.2008.00232.x

APPENDIX TABLE 1. Collection and assay methods used in the United States and Japan.

United States Japan
Biomarker Measure Method Calibration Measure Method Calibration
Systolic blood pressure Physical exam Average of 3 sets of blood pressure measurements Physical exam Average of 2 sets of blood pressure measurements
Diastolic blood pressure Physical exam Average of 3 sets of blood pressure measurements Physical exam Average of 2 sets of blood pressure measurements
Total cholesterol Blood serum Hitachi 704/717/912 Analyzer (Roche Diagnostics) Frozen serum calibration pools (Soloman Park Laboratories, Kirkland, WA) Blood serum Hitachi 7170 Seiken Liquid Abnormal
HDL cholesterol* Blood serum Hitachi 704/717/912 Analyzer (Roche Diagnostics) Frozen serum calibration pools (Soloman Park Laboratories, Kirkland, WA) Blood serum Hitachi 7170 Cholestest®N Calibrator (Sekisui Medical Co. Ltd.)
Fasting triglycerides Blood serum Hitachi 704/717/912 Analyzer (Roche Diagnostics) Calibration sera (Precical, cat no 620213) Blood serum Hitachi 7170 Multi cariblator lipid
Body mass index Physical exam Exam weight, standard anthropometry Physical exam Exam weight, standard anthropometry
Glycosylated hemoglobin Whole blood Primus Automated HPLC System/ Tosoh Alc 2.2 Plus Glycohemoglobin Analyzer Primus high performance liquid chromatography (HPLC) Whole blood BM 9030 (JEOL Ltd) RAPIDIA® Auto HbAlc (Sekisui Medical Co. Ltd.)
Albumin Blood serum Beckman Synchron LX20 Synchron Protein Calibrators (Part #450202) Blood serum Hitachi 7170 Protein Standard
*

Change in assay methods since 2001 was adjusted by correcting HDL in 2001–02 and 2005–06 using the Solomon Lab quality controls: Corrected HDL = [(Solomon Park assigned HDL value) × (Participant HDL)] /(Quality Control HDL value associated with participant sample) HDL = high density lipoprotein