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. Author manuscript; available in PMC: 2009 May 4.
Published in final edited form as: Prog Biophys Mol Biol. 2008 Mar 5;97(2-3):543–561. doi: 10.1016/j.pbiomolbio.2008.02.024

Table 3.

Global function from hybrid cardiovascular model

Non-failing heart
Failing heart
RAp LBBB VVD40 VVD0 VVD-40 LVp LBBB VVD40 VVD0 VVD-40 LVp
QRS width (ms) - 86 73 66 97 107 126 106 84 124 139
dP/dtmax (mmHg/s) LV 1630 1440 1491 1564 1577 1479 635 671 699 715 713
RV 463 406 410.3 418.7 378.4 314 236 233.7 237.0 233.7 217
SP (mmHg) LV 101.0 97.4 99.67 100.9 101.1 100.2 88.4 89.44 89.99 89.96 89.7
RV 27.7 26.2 26.56 26.86 26.24 25.1 24.6 24.50 24.48 24.43 24.0
EF (%) LV 43.8 42.3 43.3 43.5 43.3 43.1 22.0 22.6 22.8 22.8 22.4
RV 51.5 50.4 51.3 51.4 51.1 50.7 40.4 40.8 41.0 40.6 39.9
SW (mmHgml) LV 1662 1523 1619 1642 1639 1619 1314 1371 1396 1392 1361
RV 370 324 348.1 351.2 336.3 325 324 325.4 327.1 321.8 308
EDV (ml) LV 45.0 44.2 45.00 44.92 44.84 44.8 83.0 82.79 82.60 82.41 82.3
RV 37.8 37.2 37.77 37.80 37.85 37.9 45.9 46.02 46.12 46.26 46.5
EDP (mmHg) LV 13.9 14.5 13.86 13.79 13.69 13.8 15.7 15.43 15.32 15.17 15.2
RV 7.44 8.03 7.406 7.396 7.401 7.46 6.98 6.934 6.929 6.959 7.02

dP/dtmax: maximum pressure increase; EDP: end-diastolic pressure; EDV: end-diastolic pressure; EF: ejection fraction; LVp: LV pacing; Rap: synchronous stimulation; SP: systolic pressure; SW: stroke work; VVD-40, VVD0, and VVD40: biventricular pacing, 40ms LV before RV, simultaneously, and 40 ms RV before LV, respectively.