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. Author manuscript; available in PMC: 2009 May 4.
Published in final edited form as: Prog Biophys Mol Biol. 2008 Mar 5;97(2-3):543–561. doi: 10.1016/j.pbiomolbio.2008.02.024

Table 5.

Comparison between canine LBBB animal model and LBBB patients

LBBB patients LBBB dogs
QRS duration LBBB 169±16ms 123±4ms
Controls 80−100ms 69±3ms
Inter-ventricular asynchrony (RV–LV pressure difference) LBBB −50±17ms −32±7ms
Controls −5±10ms −6±9ms
Intra-ventricular asynchrony (Electrical mapping, ms) LBBB 61±15ms 26±6ms
Controls NA 5±2ms
Time to first peak systolic shortening septum to LV lateral wall delay (MR tagging) LBBB 351±92ms 173±21ms
Controls NA −27±15ms
Septal to posterior wall motion delay (SPWMD) LBBB 192±92ms 221±13ms
Controls NA 64±9ms
Echocardiography (% of controls)
    Hypertrophy 142 (%) 117 (%)±15 (%)
    LV EDV/wall mass ratio 114 (%) 110 (%)±12 (%)
    Sep/lat wall mass ratio 98 (%)−90 (%) 84±2%
Myocardial blood flow (% of mean LV) Using PET Using microspheres
    Septum 93% 83±16%
    Lateral wall 113% 118±12%