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. Author manuscript; available in PMC: 2009 Aug 26.
Published in final edited form as: Biochemistry. 2008 Jul 30;47(34):8993–9006. doi: 10.1021/bi8008399

Figure 5.

Figure 5

EM of insulin, α-synuclein, and histone aggregates. A) Fibrils of α-synuclein grown in the presence of Ficoll-70000 and 1 M TMAO (5 hours of incubation); B) oligomers of α-synuclein formed in the presence of Ficoll-70000 and 2.5 M TMAO (5 hours of incubation); C) fibrils of histones grown at pH 2.0 and PEG 10,000 (48 hours of incubation); D) oligomers and amorphous aggregates of histones formed at pH 7.5 and PEG 10,000 (48 hours of incubation); E) insulin fibrils grown at pH 2 and PEG 10,000 (20 hours of incubation); F) oligomers and amorphous aggregates of insulin formed at pH 7.5 and PEG 10,000 (20 hours of incubation). Scale bar is 100 nm.