Table 1.

Microstructural Indices of Tibial Cortical Bone in the Three Genotypes

Index	WT	Het	cKO
Cortical thickness (mm)	0.159 ± 0.007	0.147 ± 0.041*	0.130 ± 0.056*
Total area (mm2)	1.23 ± 0.09	1.62 ± 0.13*	1.55 ± 0.12*
Marrow area (mm2)	0.53 ± 0.15	0.79 ± 0.13*	0.77 ± 0.12*
Cortical area (mm2)	0.70 ± 0.15	0.83 ± 0.05*	0.78 ± 0.08
Moment of inertia (mm4)	0.128 ± 0.054	0.147 ± 0.038	0.130 ± 0.059

* p < 0.05 vs. WT; n = 8 for all groups.