Table 1. Baseline characteristics by diagnosis: all participants.
Diagnosis (n) | Control (39) | AD (38) | VAD (32) | DLB (30) | PDD (40) |
Mean Age (SD)* | 75 (6.4) | 79 (5.8) | 79 (6.2) | 76 (7.1) | 72 (6.0) |
Gender: male (%) | 21 (53.8) | 18 (47.4) | 23 (71.9) | 18 (60.0) | 26 (65.0) |
Median duration of dementia: months (IQR) | - | 36 (21–48) | 18 (9–30) | 24 (12–48) | 24 (15–48) |
Mean CAMCOG score (SD)** | 94 (4.7) | 59 (15) | 64 (18) | 59 (15) | 64 (16) |
Resident in care home n (%) | 0 (0) | 6 (15.8) | 6 (18.8) | 9 (30) | 3 (7.5) |
History of falls in previous 12 months n (%) *** | 13 (33.3) | 19 (51.4) | 21 (65.6) | 18 (69.2) | 33 (86.8) |
History of recurrent falls in previous 12 months n (%) † | 2 (5.1) | 10 (26.3) | 17 (53.1) | 12 (40.0) | 29 (72.5) |
Uses walking aid or requires assistance to walk n (%) †† | 3 (7.7) | 5 (13.2) | 9 (28.1) | 14 (46.7) | 27 (67.5) |
Cardiovascular medication n (%) ††† | 19 (48.7) | 27 (71.1) | 28 (87.5) | 20 (66.7) | 39 (97.5) |
Psychotropic medication n (%) ‡ | 5 (12.8) | 11 (28.9) | 19 (59.4) | 15 (50.0) | 20 (50.0) |
Symptomatic orthostatic hypotension n (%) ‡‡ | 0/39 (0) | 2/37 (5.4) | 3/31 (9.7) | 4/26 (15.4) | 12/38 (31.6) |
SD: Standard deviation; IQR: Inter-quartile range; AD: Alzheimer's disease; VAD: Vascular dementia; DLB: Dementia with Lewy bodies; PDD: Parkinson's disease dementia; PD: Parkinson's disease. Denominators are given for prevalence (%) where data is incomplete.
Control vs. patients p = 0.457; Control vs. AD p = 0.036; control vs. VAD p = 0.027; Control vs. DLB p = 0.945; Control vs. PDD p = 0.031.
Control vs. all patient groups p<0.001. No significant differences between patient groups.
Control vs. AD p = 0.087; control vs. VAD p = 0.009; Control vs. DLB p = 0.005; Control vs. PDD p<0.001
Control vs. AD p = 0.013; control vs. VAD p<0.001; Control vs. DLB p = 0.001; Control vs. PDD p<0.001
Control vs. AD p = 0.481; control vs. VAD p<0.024; Control vs. DLB p<0.001; Control vs. PDD p<0.001
Control vs. AD p = 0.063; control vs. VAD p = 0.001; Control vs. DLB p = 0.151; Control vs. PDD p<0.001
Control vs. AD p = 0.098; control vs. VAD p<0.001; Control vs. DLB p = 0.001; Control vs. PDD p = 0.001
Control vs. AD p = 0.234; control vs. VAD p<0.082; Control vs. DLB p<0.022; Control vs. PDD p<0.001