Skip to main content
. Author manuscript; available in PMC: 2009 Nov 5.
Published in final edited form as: J Am Chem Soc. 2008 Oct 9;130(44):14675–14683. doi: 10.1021/ja804656h

Figure 6.

Figure 6

Views of the NMR structure ensemble (backbone RMSD = 0.30 ± 0.13 Å) generated for Pr-WIpGIWTGPS. Panel A presents a view in which the twisted hairpin conformation is apparent; all heavy atoms are shown. This view also shows the I2/I5 alignment. Panel B shows two views of the Pr-C=O/Thr7 relationship in a representative structure. In the bonds-only view (right) the Me group of Thr, as well as the ethyl groups of Ile5 and the propanoyl cap, have been deleted. In the space-filling (CPK, left) view of the same region, these three alkyl groups (which effectively sequester the Thr7 OH proton from water) are included.