TABLE 3.

Predicted Mean Differences in MCPT by Level of TNF-α and TNF Receptor 1 and 2, Overall and Stratified by Age

	TNF-α			TNF Receptor 1			TNF Receptor 2
	n*	Mean Difference per Unit Change in TNF-α, mm	P	n*	Mean Difference per Unit Change in TNF Receptor 1, mm	P	n*	Mean Difference per Unit Change in TNF Receptor 2, mm	P
Overall
Unadjusted	245	−0.018	0.197	217	0.233	<0.0001	218	0.070	0.005
Adjusted for demographic factors†	239	−0.023	0.074	212	0.116	0.034	213	0.016	0.505
Adjusted for demographic and medical risk factors‡	232	−0.023	0.054	209	0.101	0.071	210	0.012	0.611
Aged <70 y
Unadjusted	153	−0.012	0.476	138	0.359	0.011	139	0.098	0.041
Adjusted for demographic factors†	147	−0.020	0.256	133	0.344	0.002	134	0.073	0.135
Adjusted for demographic and medical risk factors‡	144	−0.016	0.339	131	0.358	0.001	132	0.091	0.051
Aged ≥70 y
Unadjusted	91	−0.026	0.215	79	0.082	0.269	79	0.007	0.840
Adjusted for demographic factors†	92	−0.022	0.287	79	0.099	0.194	79	0.010	0.781
Adjusted for demographic and medical risk factors‡	88	−0.025	0.215	78	0.101	0.190	78	0.000	0.992

^*The number of subjects for each model differs slightly because not all data were available on all subjects, and those with missing values were excluded from the analyses.

^†Adjusted for age (overall model only), race-ethnicity (white non-Hispanic, black non-Hispanic, or Hispanic), and sex.

^‡Adjusted for age (overall model only), race-ethnicity (white non-Hispanic, black non-Hispanic, or Hispanic), sex, hypertension, diabetes mellitus, LDL, current cigarette smoking, and body mass index.