The effects of different doses of TGF-α (0.1, 0.25, and 0.5 μg/hour/animal) infused for seven days on activity (% of activity before infusions), food consumption (grams/week), and change in body weight (grams/week). The symbols represent average values and vertical lines standard errors. The average values for infusions with vehicle only are based on 9 hamsters and all other averages are based on 3 hamsters/dose. All three measures showed significant differences across dose. (ANOVA: Activity – F=6.08, df=17; Food Consumed – F=5.04, df=17; Weight Loss – F=6.0, df=17; P< 0.02, *P<0.05 vs vehicle-only or the lowest dose, Newman-Kuels).