Table 1.

The parameter settings and biological emphases in the five queries

	ω c	ω e	ω f	ω q	Z0	Emphasis
Query 1	0.5	0.5	0.5	0.5	0 for all	overall
Query 2	0	1	0.5	0.5	0 for all	enzyme
Query 3	1	0	0	0	0 for all	compound
Query 4	0.5	0.5	0.5	0.5	100 for "dg"and "eg", 0 otherwise	gap
Query 5	0	1	1	0	0 for all	enzyme function