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. Author manuscript; available in PMC: 2010 Mar 11.
Published in final edited form as: Structure. 2009 Mar 11;17(3):363–373. doi: 10.1016/j.str.2009.01.006

Figure 3.

Figure 3

Comparison of the obtained TFIID models.

(A) Dissection of TFIID model 3 into 4 sub-domains A, B, C1 and C2. (B) Table showing the volume occupied by the different lobes A, B, C1 and C2. The average volume (Average) of a given lobe as well as the standard deviation (σ) are shown in the last rows. Note that for lobe C2 these values were calculated from models 1, 2 and 3 only. The columns labeled “Δ/σ” represent the difference between the volume of a lobe and the average volume of that lobe normalized by the associated standard deviation. (C) Alignment of lobes A, B and C dissected from all four TFIID models showing their structural homology. (D) Fitting of TFIID model 3 into the envelope of the larger model 4 reveals two additional densities (highlighted by asterisks; *) in lobe C; colors, red, blue, yellow and brown represent lobes B, C2, C1 and A, respectively. Bar indicates 2 nm, model bottom was rotated 97° relative to top model