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Age-dependent increase in P-tau positive bodies in the dentate gyrus of mutant brain. The graph shows the number of round bodies detected with antibody AT270 in the dentate gyrus of Naglu−/− and Naglu+/− mice at 1, 3, and 6 months. A total of 6 fields from each mouse were used for counting after immunostaining as shown in Fig. 1 S and T. The bars show the mean ± SD for 3 mice.
