Table 1.
Differential gene expression in neurons of the MEC and LEC regions of the brain of Naglu−/− mice
| Accession | Gene symbol | MEC | p value | LEC | p value |
|---|---|---|---|---|---|
| NM_017372 | Lyzs | 6.93 | 0.0002 | 6.16 | 0.002 |
| NM_021281 | Ctss | 2.2 | 0.00 | 2.3 | 0.02 |
| NM_147217 | Gprc5c | 2.5 | 0.05 | 2.0 | - |
| AK083103 | Mobp | 2.2 | 0.04 | 1.2 | - |
| NM_031254 | Trem2 | 2.0 | 0.02 | 1.6 | - |
| NM_025745 | 4933407N01Rik | 1.9 | 0.02 | 1.3 | - |
| NM_026380 | Rgs8 | 1.9 | 0.00 | 1.4 | - |
| NM_022980 | Dscr1l2 | 1.8 | 0.03 | 2.0 | - |
| NM_031998 | Tsga14 | 1.8 | 0.05 | 1.1 | - |
| AK047894 | Cit | 1.8 | 0.02 | 1.2 | - |
| NM_010700 | Ldlr | 1.8 | 0.03 | 1.3 | - |
| NM_007694 | Chgb (n = 5) | 1.8 | <0.01 | 1.5 | - |
| AK038529 | Cdh4 | 3.8 | - | 2.8 | 0.04 |
| NM_001037727 | Arhgap25 | 1.3 | - | 2.7 | 0.04 |
| XM_885736 | Fat1 | 3.8 | - | 2.6 | 0.01 |
| NM_080728 | Myh7 (n = 2) | 1.0 | - | 2.3 | <0.05 |
| AK017596 | EST, unknown | 2.1 | - | 1.9 | 0.03 |
| NM_008528 | Blnk | 1.6 | - | 1.9 | 0.00 |
| NM_027518 | Gpr137c | −1.1 | - | 1.9 | 0.00 |
| NM_172443 | Tbc1d16 | 1.3 | - | 1.9 | 0.04 |
| NT_039170 | Gls | 1.3 | - | 1.9 | 0.04 |
| NM_010271 | Gpd1 | 1.3 | - | 1.9 | 0.02 |
| NM_008380 | Inhba | 1.3 | - | 1.8 | 0.04 |
| AK150790 | H2-K1 | 1.5 | - | 1.8 | 0.00 |
| AK020521 | Gorasp2 | 1.0 | - | 1.8 | 0.04 |
| AK078617 | Trps1 | 1.0 | - | −1.8 | 0.02 |
| NM_001045520 | Clint1 | 1.1 | - | −1.8 | 0.01 |
Results are expressed as an average fold change of Naglu−/− vs. Naglu+/− in 3 independent experiments (3 different pairs of animals) for MEC and LEC. Significance was calculated using paired t test (P < 0.05). The p value is not shown when significance was not reached (P > 0.05). The number of unique microarray probes for a given gene (n) is specified if greater than 1