. Author manuscript; available in PMC: 2010 Apr 1.

Published in final edited form as: Genet Epidemiol. 2009 Apr;33(3):247–255. doi: 10.1002/gepi.20376

Table III.

Vitamin A associated genes. Individual SNP Z² p-values for all vitamin A metabolizing genes generating an overall sum_logP p-value < 0.05. Risk haplotype alleles are coded 1 for major or 2 for minor allele. All SNPs included are intronic.

Gene (Sum_logP)	Dx	Effect	Vitamin A±1257μg	SNP	Z² p-value	Risk haplo type
TGFBR2 (0.028)	CL/P	Mom	< 1257	rs1835538	0.12
				rs4522809	0.0092^*	2
				rs1155708	0.917
				rs3773634	0.638
				rs876688	0.927

TGFBR2 (0.030^†)	CL/P	Child	< 1257	rs1835538	0.69^†
				rs4522809	0.0069^*^†	1
				rs1155708	1^†
				rs3773634	0.703^†
				rs876688	0.929^†

RAI1 (0.035)	CPO	Mom	< 1257	rs11656775	0.031^*	1
RAI1 (0.035)	CPO	Mom	< 1257	rs7224617	0.616

TGFB2 (0.048)	CPO	Mom	1257⁺	rs6658835	0.589
				rs2027566	1
				rs2799090	0.019^*	1
				rs2799103	0.142
				rs2000220	0.545
				rs2796813	0.443

Individual SNP Z² p-value < 0.05

^†

Families with missing genotypes were not used due to evidence of a maternal effect.