Table 1. Characteristics of Studies.
AUTHOR | YEAR | DESIGN | ALLOGRAFT | SAMPLE SIZE | MEAN AGE (years) | GENDER Male/Female (%) | CMV D+/R− (%) | INDUCTION THERAPY (%) | FK (%) | CsA (%) | MMF (%) | AZT (%) | Prednisone (%) | VALGAN DAILY DOSE (MG) | CONTROL | PROPHYLAXIS DURATION (Days) | FOLLOW UP (Months) |
Jadad Score | |||||||||||||||||
Paya C et al [7] | 2004 | Randomized | Kidney; Kidney-pancreas; Liver;Heart | 364 | 45 | 74/26 | 100 | n/a | n/a | n/a | n/a | n/a | n/a | 900 | Ganciclovir PO (3 g/day) | 100 | 6 and 12 |
Jadad = 3 | |||||||||||||||||
Khoury J et al [9] | 2006 | Randomized | Kidney | 98 | 49 | 49/51 | 30 | 97 | 98 | 2 | 68 | 0 | 100 | 900 | Preemptive | 100 | 12 |
Jadad = 2 | |||||||||||||||||
Said T et al [10] | 2007 | Randomized | Kidney | 110 | 40 | 61/39 | n/a | 100 | 45 | 35 | 100 | 0 | 100 | 900 | Ganciclovir IV (5 mg/kg/day) | 14–90 | 6 |
Jadad = 2 | |||||||||||||||||
Humar A et al [11] | 2005 | Cohort | Lung | 80 | 49 | 66/44 | 25 | 29 | 0 | 90 | 54 | 36 | 100 | 900 | Ganciclovir PO (3 g/day) | 90 | 6 and 12 |
Jadad = NA | |||||||||||||||||
Zamora M et al [12] | 2004 | Cohort | Lung | 230 | 54 | 55/45 | 21 | 0 | 0 | 100 | 0 | 100 | 100 | Ganciclovir IV (30 days)+CMVIG (3 doses)+Valgan 900 mg (N = 11); 450 mg (N = 79) | Ganciclovir IV (30 days)+CMVIG (3 doses)+Acyclovir PO 800 TID | 180–365 | 12 |
Jadad = NA | |||||||||||||||||
Weng F et al [13] | 2007 | Cohort | Kidney and Kidney-pancreas | 500 | 46 | 58/62 | 21 | 55 | 31 | 61 | 84 | 0 | 77 | 450 | Ganciclovir PO (3 g/day) | 90 | 12 |
Jadad = NA | |||||||||||||||||
Akalin E et al [14] | 2003 | Case-Control | Kidney and Kidney-pancreas | 129 | n/a | 63/37 | 13 | 47 | n/a | n/a | 100 | 0 | 100 | 450 | Ganciclovir PO (3 g/day) | 90 | 12 |
Jadad = NA | |||||||||||||||||
Keven K et al [15] | 2004 | Case-Control | Kidney and Kidney-pancreas | 211 | 49 | 61/39 | 24 | 100 | 100 | 0 | 0 | 0 | 0 | 450 | Ganciclovir PO (3 g/day) | 90–180 | 12 |
Jadad = NA | |||||||||||||||||
Park J et al [16] | 2006 | Case-Control | Liver | 109 | 50 | 53/47 | 22 | 0 | 100 | 0 | 100 | 0 | 100 | 450 | Ganciclovir PO (3 g/day) | 100 | 12 |
Jadad = NA |