Table 2.
Baseline characteristics of the study subjects (n = 15) a
| Characteristic | Value | Range |
|---|---|---|
| Age (years) | 26.9 ± 6.5 | 19−39 |
| Weight (kg) | 80.9 ± 32.5 | 50.7−160.1 |
| BMI (kg/m2) | 29.6 ± 10.7 | 19.9−53.5 |
| Systolic blood pressure (mmHg) | 108.2 ± 13.6 | 82−132 |
| Diastolic blood pressure (mmHg) | 65.7 ± 7.8 | 54−87 |
| Waist circumference (cm) | 93.5 ± 25.0 | 71−152 |
| Body fat percentage b | 33.7 ± 7.9 | 18.1−45.8 |
| Lean mass (g) b | 44,993 ± 10,065 | 33,182−67,455 |
| Fat mass (g) b | 26,128 ± 10,065 | 9,867−59,264 |
| Prolactin (ng/mL) c | 9.9 ± 6.3 | 3−24 |
| 17-hydroxyprogesterone (ng/mL) c | 0.9 ± 0.6 | 0.4−1.1 |
| TSH (mIU/mL) c | 1.7 ± 1.3 | 0.6−5.0 |
| Testosterone (ng/dL) | 59.1 ± 19.2 | 31−89 |
| SHBG (nmol/L) | 45.9 ± 33.4 | 10−131 |
| Free Androgen Index | 6.5 ± 4.2 | 1.7−19.8 |
| Fasting glucose (mg/dL) | 86.2 ± 9.2 | 75−113 |
| Fasting insulin (μU/ml) | 12.9 ± 10.8 | 4−57 |
| Cholesterol (mg/dL) c | 161.2 ± 21.6 | 110−193 |
| Triglycerides (mg/dL ) c | 108.5 ± 72.3 | 27−283 |
a
Data represent mean ± SD. BMI, body mass index; SHBG, sex hormone binding globulin; TSH, thyroid-stimulating hormone.
b
n = 14
c
Values measured at screening