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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Microcirculation. 2009 May;16(4):289–306. doi: 10.1080/10739680902801949

Figure 4. Enhanced MMP activity in the SHR Microcirculation.

Figure 4

Digital fluorescent micrographs of WKY and SHR mesenteric microvessels labeled with fluorogenic peptide substrate showing matrix metalloproteinase (MMP-2, 9) enzymatic activity. Arterioles (A) and venules (V) are visible. Note the enhanced fluorescent emission over the endothelial cells and mast cells in the SHR, an affect that is less detectable after the doxycycline treatment. Adapted from (25). Bar equals 60 μm.