Figure 4.

Nucleotide features of endonuclease genes. (A) RNA hairpin structures at the 5′ untranslated region of endonuclease ORFs in the gp41-1 (representing the very similar sequences of gp41-1–7), nrdA-5 and DnaE-1 gene loci. Initiator codons are marked by arrows, conserved putative T4 late promoter elements are boxed, and conserved sequence motifs (Supplementary Figure S4) are highlighted in grey. The expected values for motifs 1 and 2 are 1.7⁻¹⁰ and 9.9⁻³, respectively. RNA structures were calculated using the Vienna package (http://rna.tbi.univie.ac.at/cgi-bin/RNAfold.cgi), and sequence motifs were identified using the MEME program. (B) Overlapping#protein coding regions of endonuclease 3′ termini and the 5′ termini of their downstream genes.