Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Principle behind light-up probes for aptamers and their displacemnt with unconjugated small molecules: An RNA aptamer against a molecule (circle) binds a conjugate between molecule and TO dye, resulting in a fluorescent complex. Presence of free molecule in solution results in displacement of conjugate from the complex and reduction in fluorescence.
