Table 3.

Life Status and SMRs in 5-Year Survivors of the Childhood Cancer Survivor Study

Parameter	No. of Patients		SMR*	95% CI
	Alive	Dead
All patients	17,662	2,821	8.4	8.0 to 8.7
Sex
Male	9,636	1,686	6.7	6.4 to 7.0
Female	8,026	1,135	13.2	12.5 to 14.0
Age at diagnosis, years
0-4	7,361	820	9.1	8.5 to 9.8
5-9	3,984	616	8.4	7.7 to 9.1
10-14	3,475	667	7.9	7.3 to 8.5
15-20	2,842	718	7.9	7.4 to 8.5
Years of diagnosis
1970-1973	2,267	664	8.2	7.6 to 8.9
1974-1977	3,562	735	8.0	7.4 to 8.6
1978-1981	4,693	671	7.9	7.3 to 8.5
1982-1986	7,140	751	11.1	10.4 to 12.0
Survival after diagnosis, years
5-9	—	1,336	20.7	19.6 to 21.8
10-14	—	611	7.2	6.6 to 7.7
15-19	—	431	4.7	4.2 to 5.1
20-24	—	268	4.3	3.8 to 4.9
25-29	—	144	5.0	4.2 to 5.9
30-34	—	31	6.9	4.7 to 9.8
Diagnosis
Leukemia	5,482	913	10.0	9.4 to 10.7
Acute lymphoblastic	5,030	730	9.5	8.8 to 10.2
Acute myeloid	421	80	11.5	9.1 to 14.3
Other	391	103	14.7	12.0 to 17.8
CNS tumors	2,275	546	12.9	11.8 to 14.0
Astrocytomas	1,489	318	11.3	10.1 to 12.6
Medulloblastoma, PNET	424	128	17.7	14.8 to 21.1
Other CNS malignancy	362	100	14.1	11.5 to 17.1
Hodgkin's disease	2,207	510	7.8	7.1 to 8.5
Non-Hodgkin's lymphoma	1,381	143	4.4	3.7 to 5.2
Kidney tumors	1,638	97	4.6	3.8 to 5.6
Neuroblastoma	1,274	84	5.6	4.4 to 6.9
Soft tissue sarcoma	1,594	244	7.1	6.2 to 8.1
Bone tumors	1,451	284	7.8	7.0 to 8.8
Ewings sarcoma	432	136	13.3	11.2 to 15.8
Osteosarcoma	930	138	5.9	4.9 to 6.9
Other bone tumors	89	10	4.1	2.0 to 7.5

NOTE. SMRs are age-, sex, and calendar year–standardized according to National Center for Health Statistics criteria.

Abbreviations: SMR, standardized mortality ratios; PNET, primitive neuroectodermal tumor.

^*All SMRs are statistically significant at P < .01.