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. 2009 Apr 13;27(14):2374–2381. doi: 10.1200/JCO.2008.21.1839

Table 7.

Genetic Disease in Offspring of Cancer Survivors and Sibling Controls

Genetic Disease Survivor Offspring (n = 6,129)
Sibling Offspring (n = 3,101)
No. % No. %
Cytogenetic abnormality 7 0.1 6 0.2
Single-gene (Mendelian) disorder 14 0.2 8 0.3
Simple malformation 136 2.2 97 3.1
Total 157 2.6 111 3.6