FIGURE 1. P. falciparum parasite infectivities to Aotus monkeys and to their erythrocytes in vitro.
A) Parasitemias obtained in four A. nancymaae monkeys after intravenous inoculation of 1×107 GB4-parasitized erythrocytes. All infections were cured with 25 mg/kg mefloquine (arrow). B) A. nancymaae erythrocyte invasion rates by the parents and 32 independent recombinant progeny from the P. falciparum 7G8×GB4 cross. Percentage values are relative to rates of invasion into human control erythrocytes ± SEM. C) Infectivity of 10 7G8×GB4 progeny clones to A. nancymaae monkeys. All infections were cured with 25 mg/kg mefloquine (arrows).
