Skip to main content
. Author manuscript; available in PMC: 2009 May 6.
Published in final edited form as: Toxicol In Vitro. 2007 Jul 28;22(1):190–199. doi: 10.1016/j.tiv.2007.07.007

Figure 3.

Figure 3

Transport kinetics of [14C]AZT efflux at BCB. Parallel sets of Transwells with similar TEER values (for Z310 model, TEER value was 90 ± 10 Ω.cm2; for primary CP model, TEER value was 70 ± 5 Ω.cm2) were used for either [14C]sucrose (A) or [14C]AZT (B). CR/CD represents the ratio of the chemical concentrations in the receiver chamber to that in the donor chamber. Linear ranges were decided by statistical analyses of linear model fitting as well as linear regression. The resulting slopes (ΔCR/CD·Δt) were used in Eq. 1 for calculation of permeability coefficients (PB or PT), the values of which are presented in Table 3.