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. Author manuscript; available in PMC: 2010 Jan 9.

Published in final edited form as: J Mol Biol. 2008 Oct 9;385(1):91–98. doi: 10.1016/j.jmb.2008.09.078

Comparison of the performance of the mirrortree method using the full sequence (black), full sequence without the binding neighborhood (red), and sequence without the set of randomly selected columns of the same number as the binding neighborhood (blue). Figure 5a corresponds to the orthogonal speciation correction and Figure 5b corresponds to the non-orthogonal correction. Inserts show ROC curves for up to 20% false positive rate.

Comparison of the performance of the mirrortree method using the full sequence (black), full sequence without the binding neighborhood (red), and sequence without the set of randomly selected columns of the same number as the binding neighborhood (blue). Figure 5a corresponds to the orthogonal speciation correction and Figure 5b corresponds to the non-orthogonal correction. Inserts show ROC curves for up to 20% false positive rate.