. Author manuscript; available in PMC: 2010 Jan 9.

Published in final edited form as: J Mol Biol. 2008 Oct 9;385(1):91–98. doi: 10.1016/j.jmb.2008.09.078

Table 1.

Summary of ROC₅₀ and ROC_total values for all experiments. For randomized experiments we report the mean value and compute the standard deviation based on 100 trials (standard deviation in parenthesis).

Experiment	Speciation correction	ROC₅₀ (std)	ROC_total (std)
Randomly selected columns	none	0.000 (0.003)	0.391 (0.006)
Binding neighborhood	none	0.016	0.526
Full w/o rand. selected res.	none	0.189 (0.02)	0.75 (0.02)
Full w/o binding neighborhood	none	0.090	0.667
Full sequence	none	0.249	0.793
Randomly selected columns	non-orthogonal	0.16 (0.03)	0.677(0.05)
Binding neighborhood	non-orthogonal	0.309	0.88
Full w/o rand. selected res.	non-orthogonal	0.38 (0.02)	0.851(0.02)
Full w/o binding neighborhood	non-orthogonal	0.282	0.792
Full sequence	non-orthogonal	0.410	0.852
Randomly selected columns	orthogonal	0.14 (0.03)	0.645 (0.04)
Binding neighborhood	orthogonal	0.276	0.735
Full w/o rand. selected res.	orthogonal	0.31 (0.02)	0.85 (0.02)
Full w/o binding neighborhood	orthogonal	0.249	0.735
Full sequence	orthogonal	0.348	0.838