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. Author manuscript; available in PMC: 2010 Mar 2.
Published in final edited form as: Physiol Behav. 2008 Dec 7;96(3):493–504. doi: 10.1016/j.physbeh.2008.12.001

Table 2.

Basal concentrations of dopamine within the limbic and nigrostriatal systems 17 days following repeated amphetamine (2.5 mg/kg, ip.) or saline pre-treatment.

DA Concentrations (pg/µg tissue)
Region Treatment Mean±SEM F p
Central
Nucleus of
the Amygdala
Sensitized 10.7±4.7 3.667 0.055
Non-Sensitized 29.8±2.8
Control 24.3±5.9
Medial
Prefrontal
Cortex
Sensitized 1.3±0.1 2.198 0.133
Non-Sensitized 1.2±0.1
Control 1.6±0.1
Dorsal Raphe
Nucleus
Sensitized 7.0±0.7 2.156 0.138
Non-Sensitized 10.6±0.8
Control 9.4±1.0
Median Raphe
Nucleus
Sensitized 3.3±0.5 2.982 0.071
Non-Sensitized 5.0±0.3
Control 4.6±0.4
Nucleus
Accumbens
Core
Sensitized 142.3±7.5 0.363 0.700
Non-Sensitized 150.9±4.5
Control 146.9±5.8
Substantia
Nigra
Sensitized 8.4±2.1 0.524 0.599
Non-Sensitized 5.0±1.1
Control 8.2±2.0