Table 2.
Chronic phase urine podocin mRNA and podocyte-equivalents per daya
Group | n | Urine Podocin mRNA (ng/d)
|
Urine Podocyte-Equivalents per Day
|
||
---|---|---|---|---|---|
Mean ± SD | Range | Mean ± SD | Range | ||
Normal | 4 | 0.06 ± 0.10 | 0.00 to 0.21 | 552 ± 935 | 0 to 1944 |
Nonproteinurics | 5 | 0.06 ± 0.03 | 0.00 to 0.08 | 561 ± 316 | 0 to 741 |
Limited proteinurics | 4 | 1.27 ± 0.76 | 0.46 to 2.14 | 11,782 ± 7056 | 4259 to 19814 |
Progressors | 8 | 14.04 ± 11.22b | 11.00 to 36.00 | 129,977 ± 103,916b | 24,074 to 333,333 |
Values for podocyte-equivalents per day were calculated using a recovery rate of 0.03% (see the Concise Methods section).
P < 0.01 compared with the data sets above in that column. These data assume that podocin mRNA in detached podocytes remains constant and similar to that of glomerular podocytes.