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Outline of a Surface Plasmon Resonance (SPR) system utilising a Kretschman-Raether configuration. A system with this configuration facilitates label-free detection of biomolecules that bind in real-time. Biomolecules within the sample bind to ligands immobilised on the gold surface causing a change in the levels of the surface plasmon signals. Analysis of this change enables determination of both kinetic and analyte concentrations.
