Table 3.
Antimicrobial susceptibility of diarrhoeagenic E. coli isolated from patients and controls from Al-Adan and Al-Farwaniya hospitals, Kuwait
| Organism (n)/antibiotic | MIC (μg/ml) | % Resistant | ||
|---|---|---|---|---|
| Range | MIC50 | MIC90 | ||
| EPEC a(37) | ||||
| Amikacin | 0.75 – 3 | 1.5 | 1.5 | 0 |
| Ampicillin | 3.0 – >256 | 4 | >256 | 45.9 |
| Ampicillin/sulbactam | 0.023 – 64 | 3 | 16 | 29.7 |
| Aztreonam | 0.023 – 24 | 0.047 | 0.094 | 5.4 |
| Cefotaxime | 0.047 – >256 | 0.064 | 0.094 | 5.4 |
| Chloramphenicol | 0.032 – >256 | 4 | 8 | 8.1 |
| Ciprofloxacin | 0.006 – 0.25 | 0.008 | 0.125 | 0 |
| Gentamicin | 0.004 – 64 | 0.38 | 1 | 8.1 |
| Imipenem | 0.094 – 0.25 | 0.19 | 0.19 | 0 |
| Tetracycline | 0.5 – 192 | 1.5 | 96 | 40.5 |
| Tircacillin/clavulanic acid | 0.75 – 24 | 2 | 12 | 5.41 |
| Trimethoprim | 0.19 – >32 | 1 | >32 | 43.2 |
| ETEC b(9) | ||||
| Amikacin | 1 – 8 | 2 | 2 | 0 |
| Ampicillin | 2 – >256 | >256 | >256 | 66.7 |
| Ampicillin/sulbactam | 1.5 – 24 | 4 | 24 | 33.3 |
| Aztreonam | 0.023 – 32 | 0.032 | 0.047 | 11.1 |
| Cefotaxime | 0.047 – >256 | 0.064 | 3 | 11.1 |
| Chloramphenicol | 2 – 8 | 4 | 8 | 0 |
| Ciprofloxacin | 0.004 – >32 | 0.012 | 0.032 | 11.1 |
| Gentamicin | 0.25 – 128 | 1.5 | 2 | 11.1 |
| Imipenem | 0.094 – 0.75 | 0.19 | 0.5 | 0 |
| Tetracycline | 1 – 96 | 1.5 | 96 | 33.3 |
| Tircacillin/clavulanic acid | 1.5 – 12 | 2 | 8 | 0 |
| Trimethoprim | 0.19 – >32 | 0.38 | >32 | 22.2 |
| EAEC c (9) | ||||
| Amikacin | 1 – 4 | 2 | 2 | 0 |
| Ampicillin | >256 – >256 | >256 | >256 | 100 |
| Ampicillin/sulbactam | 4 – 16 | 12 | 16 | 55.6 |
| Aztreonam | 0.016 – 32 | 0.094 | 12 | 33.3 |
| Cefotaxime | 0.032 – >256 | 0.19 | >256 | 44.4 |
| Chloramphenicol | 3 – >256 | 4 | 8 | 11.1 |
| Ciprofloxacin | 0.004 – 4 | 0.008 | 0.19 | 11.1 |
| Gentamicin | 0.38 – 48 | 1 | 32 | 22.2 |
| Imipenem | 0.094 – 0.19 | 0.19 | 0.19 | 0 |
| Tetracycline | 1.5 – >256 | 96 | 192 | 88.9 |
| Tircacillin/clavulanic acid | 1 – 24 | 12 | 12 | 11.1 |
| Trimethoprim | 0.38 – >32 | >32 | >32 | 77.8 |
| EIEC d(3) | ||||
| Amikacin | 1.5 – 2 | 1.5 | 2 | 0 |
| Ampicillin | 1.5 – 4 | 3 | 4 | 0 |
| Ampicillin/sulbactam | 1 – 2 | 1.5 | 2 | 0 |
| Aztreonam | 0.032 – 0.064 | 0.047 | 0.064 | 0 |
| Cefotaxime | 0.032 – 0.047 | 0.047 | 0.047 | 0 |
| Chloramphenicol | 3 – 4 | 4 | 4 | 0 |
| Ciprofloxacin | 0.004 – 0.125 | 0.094 | 0.125 | 0 |
| Gentamicin | 0.19 – 0.75 | 0.5 | 0.75 | 0 |
| Imipenem | 0.19 – 0.19 | 0.19 | 0.19 | 0 |
| Tetracycline | 32 – 96 | 96 | 96 | 100 |
| Tircarcillin/clavulanic acid | 0.38 – 1.5 | 1.5 | 1.5 | 0 |
| Trimethoprim | >32 – >32 | >32 | >32 | 100 |
aEnteropathogenic E. coli bEnterotoxigenic E. coli cEnteroaggregative E. coli dEnteroinvasive E. coli