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. 2009 May;127(1):62–72. doi: 10.1111/j.1365-2567.2008.02933.x

Figure 6.

Figure 6

Tumour necrosis factor receptor 2 (TNF-R2)-mediated signals contribute to increased transforming growth factor (TGF)-β secretion by tolerance-inducing TGF-β-treated antigen-presenting cells (APCs). Culture supernatants were collected at 24-hr intervals from APCs cultured in the absence or presence of TGF-β and anti-TNF-R1 blocking antibody or isotype control antibody as described in the Materials and methods. The total TGF-β content of these supernatants was determined using a bioassay.